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Americans worry more about the cost and availability of health care than any other major societal issue. Clarity in treatment costs could help alleviate stress.

Health Care & Law

Use of Regulations, Laws, Standards, and Best Practices When Prosecuting and Defending Hospitals in Drug Injury Lawsuits

The authors underscore the importance of understanding standards and procedures as they discuss two lawsuits that arose from drug injury.

Case Report

Reversal of Dabigatran Bleeding and Coagulopathy Using Idarucizumab in a Patient With Acute Kidney Injury

After being treated with idarucizumab, coagulation parameters in a patient with AKI reverted to normal within 24 hours.

Pipeline Plus

Promising Multiple Sclerosis Agents In Late-Stage Development

Developing drugs with enhanced safety profiles and improving treatment affordability are vital for patients with MS. The author reviews some encouraging new agents in late-stage development.

The Extraordinary Importance of Sleep

The Detrimental Effects of Inadequate Sleep on Health and Public Safety Drive an Explosion of Sleep Research

New sleep deprivation studies confirm the relationship between inadequate sleep and a wide range of disorders, such as hypertension, obesity and type-2 diabetes, cardiovascular disease, impaired immune functioning, and more.

A Bitter Pill to Swallow: Why Medication Safety Is Critical in Hepatitis C Treatment

Treating patients with HCV provides many opportunities for medication errors to occur. These may involve regimen selection, adherence, dispensing, and drug–drug interactions. The authors offer ten safety recommendations.

Departments

Medication Errors

Partially Filled Vials and Syringes in Sharps Containers Are a Key Source of Drug Diversion

Leftover or improperly discarded drugs are easy prey for diversion and are fueling the opioid abuse epidemic. ISMP offers safe practice recommendations to prevent drug misuse.

Prescription: Washington

P&T Committees Get New Leeway to Control Part C and Part D Drug Costs

As the door opens to more step therapy and indication-based formularies, P&T committees must walk a fine line between managing treatment costs and providing access to critical drugs.

Drug and Device News December 2018

Approvals, new indications, regulatory activities, and more

Pharmaceutical Approval Update December 2018

Mulpleta (lusutrombopag) for thrombocytopenia; ajovy (fremenezumab-vfrm) for migraine; takhzyro (lanadelumab-flyo) for hereditary angioedema attacks

Drug Forecast

Ertugliflozin (Steglatro): A New Option for SGLT2 Inhibition

Steglatro (ertugliflozin) for glycemic control in adults with type-2 diabetes mellitus

Research Briefs December 2018